Haematology

Hematology and Oncology: skepticism 10 The correct respond is C Educational Objectives Rec all(prenominal) the subroutine of slant ray of spark prior(prenominal) to transfusion. inspection The sole basis for blood irradiation is to stay fresh on transfusion-related graft-versus-host disease (GVHD) in patient ofs at encounter for it. Transfusion-related GVHD has a high gear wheel mortality rate. Not yet are the liver, skin, and gastrointestinal convenience under immunologic set on, besides the recipients bone marrow is as well destroyed by the giver T cells. da Gamma irradiation of cellular blood products interdicts transfusion-related GVHD by rendering donor T cells dead and unable(predicate) of mounting a GVHD response. The point employ is between 25 and 50 Gy. Higher demigods may interrupt with the function or survival of red cells and platelets. Leukocyte decrease is non sufficient for this purpose be set it leaves croupe too m all cells. jibe at this dose has no effect on the transmittance of cytomegalovirus (or whatsoever pathogen), alloimmune sensitization, or leukocyte antigenicity. Although the cells are nonviable and provide non cause a sustained attack against the host, they nonify still dilate cytokine. Therefore, irradiation will not prevent febrile reactions. slam has no effect on any of the mechanisms of transfusion-induced hemolysis.

Hematology and Oncology:Question 11 The correct answer is E Educational Objectives look at the appropriate timing for a work-up for a transmissible hypercoagulable state. Critique No testing is prerequisite; the patient should be started on anticoagulation therapy. Although her family history suggests that she has an underlying hereditary reproach predisposing to venous thromboembolism, it is incredible that she has the factor V Leiden or factor II G2021 0A transition because these abnormalities are not set up in indigene Asiatic populations. It is possible that she has a lack of protein C, protein 5, or antithrombin III, but it is not advisable to test for these abnormalities...If you demand to get a to the full essay, order it on our website: Ordercustompaper.com

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